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2026-05-08

2026-05-09

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Hotels in San Diego near Santa Fe Depot

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371 properties found

  • The Guild Hotel, San Diego Downtown, A Tribute Portfolio Hotel

    500 West Broadway, San Diego, United States

    0.2 km to Santa Fe Depot (Show map)

    Featuring Wi-Fi in public areas, The Guild Hotel, San Diego Downtown, A Tribute Portfolio Hotel is an 11-minute walk from the Little Italy. Boasting a fitness club, the hotel is in the very heart of…

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    From US$ 49
    price for 1 night
    Book Now From US$ 49
  • Electra Building 2Bed - Views Pool Sauna Spa

    700 West E Street, San Diego, United States

    0.2 km to Santa Fe Depot (Show map)

    Electra Building 2Bed - Views Pool Sauna Spa San Diego villa is located around 5 minutes' walk from American Plaza and offers guests to relish a patio as well as a swimming pool. This San Diego…

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  • Panoramic Bay And City Views - 2Br, Pool, Gym, Parking

    700 West E Street #3303, San Diego, United States

    0.2 km to Santa Fe Depot (Show map)

    Panoramic Bay And City Views - 2Br, Pool, Gym, Parking San Diego villa is merely a 5-minute walk from the Arredon Art gallery, offering guests to unwind at a Jacuzzi and a sauna.

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  • Intercontinental San Diego By Ihg

    901 Bayfront Court, San Diego, United States

    0.2 km to Santa Fe Depot (Show map)

    The 5-star Intercontinental San Diego By Ihg hotel sits just a 9-minute walk from USS Midway Interactive Museum and offers a convenience shop and a restaurant. Situated in the vicinity of the Little…

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    From US$ 260
    price for 1 night
    Book Now From US$ 260
  • Residence Inn By Marriott San Diego Downtown/Bayfront

    900 Bayfront Court, San Diego, United States

    0.2 km to Santa Fe Depot (Show map)

    Located approximately 400 metres from the Broadway Pier, the charming Residence Inn By Marriott San Diego Downtown/Bayfront offers Wi-Fi in public areas and a charging station for electric vehicles.

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    From US$ 276
    price for 1 night
    Book Now From US$ 276
  • The Westin San Diego Bayview

    400 West Broadway, San Diego, United States

    0.2 km to Santa Fe Depot (Show map)

    Located approximately 25 minutes' walk from the Petco Park and a mere 0.9 km from Little Italy Mercato Farmers' Saturday Market, the smoke-free The Westin San Diego Bayview hotel offers a ballroom…

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    From US$ 197
    price for 1 night
    Book Now From US$ 197
  • SpringHill Suites San Diego Downtown/Bayfront

    900 Bayfront Court, San Diego, United States

    0.2 km to Santa Fe Depot (Show map)

    Situated just 6 minutes' walk from San Diego Aircraft Carrier, the 3-star smoke-free Springhill Suites By Marriott San Diego Downtown/Bayfront hotel features a sun terrace and a shared lounge. This…

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    From US$ 260
    price for 1 night
    Book Now From US$ 260
  • The Chadwick

    646 A Street, San Diego, United States

    0.3 km to Santa Fe Depot (Show map)

    The Chadwick Hotel San Diego gives quick access to American Plaza, situated merely a 5-minute walk away.

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    From US$ 153
    price for 1 night
    Book Now From US$ 153
  • Hotel Republic San Diego, Autograph Collection

    421 West B Street, San Diego, United States

    0.3 km to Santa Fe Depot (Show map)

    Located 2.5 km from the San Diego Zoo, Hotel Republic San Diego, Autograph Collection is 5 minutes' stroll from the Museum of Contemporary Art. Featuring 284 rooms with views of the city, the hotel…

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    From US$ 126
    price for 1 night
    Book Now From US$ 126
  • Little Italy Marina Condo By The Ocean

    1325 Pacific Highway 1603, San Diego, United States

    0.3 km to Santa Fe Depot (Show map)

    Situated in the centre of San Diego, the beachfront 2-bedroom Little Italy Marina Condo By The Ocean San Diego is just 6 minutes' walk from the 1863 sailing Star of India Ship. At the 139 m²…

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  • Le Meridien San Diego Downtown

    501 West A Street, San Diego, United States

    0.3 km to Santa Fe Depot (Show map)

    Le Meridien San Diego Downtown hotel is situated in a business area of San Diego, 17 minutes' walk from Tuna Harbor Bayside Park and 3.1 km from the Coronado Island. Located within a few blocks of…

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    From US$ 517
    price for 1 night
    Book Now From US$ 517
  • Bay Views & Gaslamp/Little Italy/Convention 1Bd

    801 West F Street, San Diego, United States

    0.3 km to Santa Fe Depot (Show map)

    The 67 m² Bay Views & Gaslamp/Little Italy/Convention 1Bd Apartment San Diego is situated right in the centre of San Diego, only 1.2 km from Spreckels Theatre. Staying in the apartment, nestled in…

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  • Kasa Little Italy San Diego

    1331 Columbia St, San Diego, United States

    0.4 km to Santa Fe Depot (Show map)

    The smoke-free Kasa Little Italy San Diego hotel sits a mere 6 minutes' walk from the Little Italy and offers a shared lounge and luggage storage. Standing just around the corner from the Santa Fe…

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    From US$ 394
    price for 1 night
    Book Now From US$ 394
  • Downtown San Diego Condo 1 Mi To Gaslamp Quarter

    701 Kettner Blvd Unit 149, San Diego, United States

    0.4 km to Santa Fe Depot (Show map)

    The 102 m² Downtown San Diego Condo 1 Mi To Gaslamp Quarter is located 3 km from the San Diego Zoo and 18 minutes' walk from the Maritime Museum of San Diego. Situated in the vicinity of the Seaport…

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  • Best Western Plus Bayside Inn

    555 W Ash Street, San Diego, United States

    0.4 km to Santa Fe Depot (Show map)

    Featuring Wi-Fi in public areas, Best Western Plus Bayside Inn San Diego is an 18-minute walk from Childrens Public Park. Boasting a gym, this inn is in the centre of the city, a short way from the…

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    From US$ 153
    price for 1 night
    Book Now From US$ 153
  • Carte Hotel San Diego Downtown, Curio Collection By Hilton

    401 W Ash Street, San Diego, United States

    0.4 km to Santa Fe Depot (Show map)

    Situated nearly 10 minutes' walk from Spreckels Theatre, the convenient Carte Hotel San Diego Downtown, Curio Collection By Hilton features Wi-Fi in public areas and a private parking lot on site.

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    From US$ 254
    price for 1 night
    Book Now From US$ 254
  • Wyndham San Diego Bayside

    1355 North Harbor Drive, San Diego, United States

    0.4 km to Santa Fe Depot (Show map)

    The perfect Wyndham San Diego Bayside hotel centrally stands approximately 400 metres from San Diego County Administration Building, offering a ballroom and a banquet hall for shared gatherings.

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    From US$ 124
    price for 1 night
    Book Now From US$ 124
  • The Sofia Hotel

    150 West Broadway, San Diego, United States

    0.4 km to Santa Fe Depot (Show map)

    The 4-star The Sofia Hotel San Diego, located in the Seodaemun-Gu district, just 1.2 km from the primary San Diego Convention Center, offers cars for rent. Boasting a location within reach of the New…

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    From US$ 126
    price for 1 night
    Book Now From US$ 126
  • Italyhaus

    350 West Ash Street, San Diego, United States

    0.5 km to Santa Fe Depot (Show map)

    Located just 550 metres from Little Italy Mercato Farmers' Saturday Market and the historical sailing Star of India Ship, the spacious 85 m² Italyhaus Apartment San Diego features views of the city.

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  • The Bristol Hotel San Diego

    1055 First Avenue, San Diego, United States

    0.5 km to Santa Fe Depot (Show map)

    Providing 114 rooms, the boutique The Bristol Hotel San Diego is around a 25-minute walk from the lush park "Botanical Building". Featuring a restaurant, the 4-star hotel is located in the vicinity…

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    From US$ 126
    price for 1 night
    Book Now From US$ 126
  • Embassy Suites By Hilton San Diego Bay Downtown

    601 Pacific Highway, San Diego, United States

    0.5 km to Santa Fe Depot (Show map)

    Situated a mere 1.4 km from the 2.7-acre Park at the Park and approximately 15 minutes' walk from the shopping mall "Westfield Horton Plaza", the classic Embassy Suites By Hilton San Diego Bay…

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    From US$ 228
    price for 1 night
    Book Now From US$ 228
  • Kettner Row 2

    1525 Kettner Blvd Unit C, San Diego, United States

    0.5 km to Santa Fe Depot (Show map)

    The 1-bedroom Kettner Row 2 Villa San Diego offers proximity to such city sites as the historical sailing Star of India Ship, located only 6 minutes' walk away.

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    From US$ 128
    price for 1 night
    Book Now From US$ 128
  • Kettner Row 1

    1525 Kettner Blvd Unit B, San Diego, United States

    0.5 km to Santa Fe Depot (Show map)

    The 1-bedroom Kettner Row 1 Villa San Diego offers proximity to such city sites as Little Italy Mercato Farmers' Saturday Market, located only a 5-minute walk away.

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    From US$ 253
    price for 1 night
    Book Now From US$ 253
  • Little Italy, Close To Everything

    1401 Union St 2804, San Diego, United States

    0.5 km to Santa Fe Depot (Show map)

    Located merely 1 km from Copley Symphony Hall, Little Italy, Close To Everything San Diego apartment is approximately a 25-minute walk from a top family-friendly place like the San Diego Zoo. Guests…

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  • Hampton Inn San Diego Downtown

    1531 Pacific Highway, San Diego, United States

    0.5 km to Santa Fe Depot (Show map)

    Nestled in the Seodaemun-Gu district of San Diego, about 25 minutes' walk from the Museum of Photographic Arts, the 3-star smoke-free Hampton Inn San Diego Downtown features a rooftop pool and views…

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    From US$ 149
    price for 1 night
    Book Now From US$ 149
  • Little Italy Urban Designer Loft Parking, Wandd, Ac

    1601 Kettner Boulevard Unit 16, San Diego, United States

    0.6 km to Santa Fe Depot (Show map)

    Situated merely a 5-minute stroll from Little Italy Mercato Farmers' Saturday Market, Little Italy Urban Designer Loft Parking, Wandd, Ac Villa San Diego offers easy access to numerous tourist spots…

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  • Rooftop With Views Modern Little Italy Townhome

    1576 State St, San Diego, United States

    0.6 km to Santa Fe Depot (Show map)

    Located merely 6 minutes' walk from the Vitreum, the 2-bedroom Rooftop With Views Modern Little Italy Townhome San Diego villa offers quick access to various city attractions in the vicinity.

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    From US$ 854
    price for 1 night
    Book Now From US$ 854
  • The Westin San Diego Gaslamp Quarter

    910 Broadway Circle, San Diego, United States

    0.6 km to Santa Fe Depot (Show map)

    Located only 1.6 km from the Maritime Museum of San Diego, the 4-star The Westin San Diego Gaslamp Quarter hotel is only a 5-minute walk from Spreckels Theatre. Nestled in the Seodaemun-Gu district…

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    From US$ 143
    price for 1 night
    Book Now From US$ 143
  • Sonder The Bungalows

    1525 Union Street, San Diego, United States

    0.7 km to Santa Fe Depot (Show map)

    Sonder The Bungalows San Diego hotel is a great place to stay in the Marina district, about a 25-minute walk from the historical naval aircraft carrier USS Midway Museum.

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    From US$ 134
    price for 1 night
    Book Now From US$ 134
  • Allura Little Italy - 2 Bedroom In Downtown'S Top Spot

    1670 Kettner Boulevard, San Diego, United States

    0.7 km to Santa Fe Depot (Show map)

    To enjoy your vacation in San Diego, stay at the spacious 70 m² Allura Little Italy - 2 Bedroom In Downtown'S Top Spot San Diego apartment, which is about 700 metres from the Santa Fe Depot and…

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  • The Westgate Hotel

    1055 Second Ave, San Diego, United States

    0.7 km to Santa Fe Depot (Show map)

    Situated 16 minutes' walk from the 2.7-acre Park at the Park, the 4-star The Westgate Hotel San Diego offers a 24-hour business centre with a range of business amenities. Located 500 metres from the…

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    From US$ 172
    price for 1 night
    Book Now From US$ 172
  • The Pacific

    1655 Pacific Highway, San Diego, United States

    0.7 km to Santa Fe Depot (Show map)

    Situated only 1.6 km from the Seaport Village, the 2-star The Pacific Motel San Diego features Wi-Fi throughout the property, and a private parking lot on site. The motel, located right around the…

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    From US$ 79
    price for 1 night
    Book Now From US$ 79
  • Urban Boutique Hotel- Little Italy, Downtown San Diego

    1654 Columbia Street, San Diego, United States

    0.7 km to Santa Fe Depot (Show map)

    Urban Boutique Hotel- Little Italy, Downtown San Diego provides 54 air-conditioned rooms and sits 7 minutes' walk from the San Diego Firehouse Museum. The hotel features both Wi-Fi in the rooms and…

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    From US$ 118
    price for 1 night
    Book Now From US$ 118
  • San Diego'S Diamond

    1501 Front St, San Diego, United States

    0.7 km to Santa Fe Depot (Show map)

    Offering a Jacuzzi, San Diego'S Diamond villa is located around a 25-minute walk from the Ruocco Park. Guests can enjoy snorkelling, canoeing, and bowling at this property, located 3.2 km from the…

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  • Down Town Condo With Gym Pool Bbq Jacuzzi

    1501 Front Street, San Diego, United States

    0.7 km to Santa Fe Depot (Show map)

    Offering a hot tub for guests to unwind, Down Town Condo With Gym Pool Bbq Jacuzzi San Diego villa is located only 6 minutes' walk from the Little Italy.

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  • The Us Grant, A Luxury Collection Hotel, San Diego

    326 Broadway, San Diego, United States

    0.7 km to Santa Fe Depot (Show map)

    Located in an old part of San Diego and nearly minutes' walk from North Embarcadero, the deluxe The Us Grant, A Luxury Collection Hotel, San Diego offers car rentals to help guests explore the area.

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    From US$ 190
    price for 1 night
    Book Now From US$ 190
  • La Pensione Hotel

    606 West Date Street, San Diego, United States

    0.7 km to Santa Fe Depot (Show map)

    The smoke-free La Pensione Hotel San Diego is a great place in a business area of San Diego, which stands about a 25-minute walk from the Gaslamp Museum at the Davis-Horton House Museum. This 3-star…

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    From US$ 108
    price for 1 night
    Book Now From US$ 108
  • Tucasa Luxury 4 Story Villa In Downtown San Diego Little Italy

    343 West Date Street, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Located only a 6-minute stroll from the iron-hulled sailing Star of India Ship, Tucasa Luxury 4 Story Villa In Downtown San Diego Little Italy gives easy access to various tourist attractions in the…

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    From US$ 861
    price for 1 night
    Book Now From US$ 861
  • Residence Inn By Marriott San Diego Downtown

    1747 Pacific Highway, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Located a mere 1.6 km from the Seaport Village, the 3-star smoke-free Residence Inn By Marriott San Diego Downtown features Wi-Fi in public areas and a private parking lot on site. Boasting a heated…

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    From US$ 149
    price for 1 night
    Book Now From US$ 149
  • Cheerful 4Bd Home In The Heart

    223 West Date Street 2, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    The 3-bedroom Cheerful 4Bd Home In The Heart San Diego offers proximity to nearby tourist spots, such as the San Diego Chinese Historical Museum, situated around 20 minutes' walk away.

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    From US$ 551
    price for 1 night
    Book Now From US$ 551
  • Bright, Spacious 4 Bd In The Heart Of Little Italy

    223 W Date St, San Diego, Ca 92101, Usa Villa 1, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    The 3-bedroom Bright, Spacious 4 Bd In The Heart Of Little Italy San Diego villa provides easy access to various city attractions, such as the Little Italy Street Sign, situated approximately 5…

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    From US$ 1212
    price for 1 night
    Book Now From US$ 1212
  • Lovely Studio In The Heart Of Little Italy

    223 West Date Street 3, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    The 1-bedroom Lovely Studio In The Heart Of Little Italy San Diego villa offers quick access to such tourist spots as the Little Italy Street Sign, situated merely a 5-minute walk away.

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    From US$ 432
    price for 1 night
    Book Now From US$ 432
  • Vantaggio Suites

    State Street 1736, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Vantaggio Suites San Diego hotel features 288 rooms and lies around a 25-minute walk from Childrens Public Park.

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  • Little Italy Inn - Limited Service Apart Hotel

    1736 State Street, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Situated fairly close to the Our Lady of the Rosary Catholic Church, the 2-star Little Italy Inn - Limited Service Apart Hotel San Diego features Wi-Fi throughout the property and private car parking…

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    From US$ 114
    price for 1 night
    Book Now From US$ 114
  • International Travelers House Downtown San Diego - Adults Only

    230 W Cedar Street, San Diego, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Featuring a shared lounge, International Travelers House Downtown San Diego - Adults Only hostel is situated in the centre of San Diego, merely a 6-minute walk from San Diego Opera. Featuring Wi-Fi…

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  • 1900'S Victorian Home Sleeps 22 8Bdrm 3Bath

    205 West Date Street, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Located merely 6 minutes on foot from Influx Cafe Little Italy, the 3-bedroom 1900'S Victorian Home Sleeps 22 8Bdrm 3Bath San Diego gives easy access to various tourist attractions in the area.

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    From US$ 776
    price for 1 night
    Book Now From US$ 776
  • 1920'S Remodeled Cottage In The Heart Of Little Italy

    1662 Front Street, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Situated about a 25-minute walk from USS Midway Interactive Museum, 1920'S Remodeled Cottage In The Heart Of Little Italy San Diego provides access to numerous tourist attractions in the area.

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    From US$ 189
    price for 1 night
    Book Now From US$ 189
  • Ith San Diego Adventure Hostel (Adults Only)

    230 W Cedar Street, San Diego, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Situated merely a 7-minute stroll from Little Italy Mercato Farmers' Saturday Market, Ith San Diego Adventure Hostel offers a shared lounge and various recreational opportunities for added enjoyment.…

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    From US$ 45
    price for 1 night
    Book Now From US$ 45
  • Motel 6 San Diego, CA - Downtown

    1546 2nd Ave I-5/San Diego Freeway at 6th Avenue, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Offering a vending machine and a lift, the smoke-free Motel 6-San Diego, Ca - Downtown is located only 450 m from Casa De Oracion. This 3-star motel also provides guests with Wi-Fi, available in…

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    From US$ 70
    price for 1 night
    Book Now From US$ 70
  • 1Bd Remodeled Craftsman Cottage Free Parking Heart Of Little Italy

    1668 Front Street, San Diego, United States

    0.8 km to Santa Fe Depot (Show map)

    Located just 0.8 km from Santa Fe Depot railway station, 1Bd Remodeled Craftsman Cottage Free Parking Heart Of Little Italy San Diego is a mere 5 minutes' walk from the Little Italy. Guests can make…

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